In the BiKi Life Sciences tutorials, we will play with CDK2 and Staurosporine. In particular, we will learn how to study the protein-ligand complex stability via plain MD followed by clustering using the BiKi GUI. In a second phase instead, we will learn how to set up an MD Binding simulation: by this BiKi unique algorithm, we will able to place Staurosporine in the solvent and accelerate the dynamical binding process of several orders of magnitudes with respect to plain MD.